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Readability
Perhaps most fundamentally, content should be understandable by the people who are trying to read it.
Headings
Use headings to break up content and improve readability
Headings should be accurate and informative
Headings should convey a clear and accurate structural outline of the content of a webpage
Headings should not skip hierarchical levels.
Links
Links must have some text associated to them
if you are making an image a link, ensure the image has useful alt text.
Link text should be descriptive
Links should make sense out of context and out of sequential order.
Providing Emphasis
Using visual emphasis appropriately is helpful in conveying meaning, but assistive technology doesn't always read out formatting, so if the emphasis is critical to understand the text — then you'll need to find another way to communicate emphasis.
Quotations
Do use the blockquote element for long quotations.
Do not use the blockquote element to apply visual styling alone
For inline quotations, quotations marks are sufficient.
Multimedia
Alternative text for images
Alternative text is essential for conveying non-text information. You should describe the purpose of the images in as few words as possible.